2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

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Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-147002
    7-O-Methyl Ivermectin B1a
    		Inhibitor
    7-O-Methyl Ivermectin B1a is an analogue of Ivermectin B1a (HY-126937).
    7-O-Methyl Ivermectin B1a
  • HY-155087
    Anticancer agent 140
    		Inhibitor
    Anticancer agent 140 (Compd 3) is a compound with potential anticancer and antiparasitic activities.
    Anticancer agent 140
  • HY-107771R
    Fluensulfone (Standard)
    		Inhibitor
    Propane sultone (Standard) is the analytical standard of Propane sultone. This product is intended for research and analytical applications. Propane sultone is a versatile intermediate. Propane sultone is utilized as an additive in the electrolyte in lithium battery. Propane sultone combines with cellulose and carbohydrate, that can be used in sizing, printing and textile. Propane sultone is utilized in dye manufacture.
    Fluensulfone (Standard)
  • HY-N2381R
    Menthone (Standard)
    		Inhibitor
    Menthone (Standard) is the analytical standard of Menthone. This product is intended for research and analytical applications. Menthone, an orally active monoterpene that can be isolated from plants and Mentha oil with antibacterial, antitumor, antioxidation, and antivirus properties. Menthone is a main volatile component of the essential oil, and has anti-Inflammatory properties in Schistosoma mansoni infection and rheumatoid arthritis.
    Menthone (Standard)
  • HY-156082
    RyRs activator 3
    		Inhibitor
    RyRs activator 3 (compound A4) is an effective insecticide against diamondback moths (M. separata) and diamondback moths (P. xylostella). The LC50 value of RyRs activator 3 against diamondback moth is 3.27 mg/L. RyRs activator 3 can bind to ryanodine receptor, increase cytoplasmic Ca2+ concentration, and produce biological toxicity.
    RyRs activator 3
  • HY-W012732R
    Isoquinoline (Standard)
    		Inhibitor
    Isoquinoline (Standard) is the analytical standard of Isoquinoline. This product is intended for research and analytical applications. Isoquinoline is an analog of pyridine. Isoquinoline structural-based alkaloids, such as tropoloisoquinoline, phthalideisoquinoline, and naphthylisoquinoline has anti-cancer activities.
    Isoquinoline (Standard)
  • HY-N10255
    Trypacidin
    Trypacidin is the conidia-bound metabolite with antiprotozoal activity. Trypacidin has a protective function against phagocytes both in the environment and during the infection process.
    Trypacidin
  • HY-A0148
    Halofantrine
    		Inhibitor
    Halofantrine (SKF-102886 free base) is a highly lipophilic antimalarial active against Chloroquine-resistant strains of Plasmodium falciparum. Halofantrine blocks HERG potassium channels.
    Halofantrine
  • HY-W031727S1
    Hydroxychloroquine-d5
    Hydroxychloroquine-d5 is the deuterium labeled Hydroxychloroquine[1]. Hydroxychloroquine is a synthetic antimalarial agent which can also inhibit Toll-like receptor 7/9 (TLR7/9) signaling. Hydroxychloroquine is efficiently inhibits SARS-CoV-2 infection in vitro[2][3][4].
    Hydroxychloroquine-d<sub>5</sub>
  • HY-N10899
    Bruceine J
    		Inhibitor
    Bruceine J, a quassinoid, is a nature product that could be isolated from fruits of Br. jaVanica. Bruceine J has anti-Babesial activity.
    Bruceine J
  • HY-N10197
    Pulixin
    		Inhibitor
    Pulixin prevents FREP1 from binding to P. falciparum-infected cell lysate. Pulixin blocks the transmission of the parasite to mosquitoes with an EC50 of 11 µM. Pulixin also inhibits the proliferation of asexual-stage P. falciparum with an EC50 of 47 nM.
    Pulixin
  • HY-B0806S1
    Proguanil-d4
    Proguanil-d4 is the deuterium labeled Proguanil[1]. Proguanil, an antimalarial proagent, is metabolized to the active metabolite Cycloguanil (HY-12784). Proguanil is a dihydrofolate reductase (DHFR) inhibitor[2][3].
    Proguanil-d<sub>4</sub>
  • HY-N9179
    3′,4′,5′,5,6,7-Hexamethoxyflavone
    		Inhibitor
    3′,4′,5′,5,6,7-Hexamethoxyflavone is a flavonoid with antiprotozoal activity. 3′,4′,5′,5,6,7-Hexamethoxyflavone inhibits trypanosoma bruceirhodesiense with IC50 of 21.3 μM (8.58 g/mL).
    3′,4′,5′,5,6,7-Hexamethoxyflavone
  • HY-133004
    Fenbutatin oxide
    		Inhibitor
    Fenbutatin oxide is an organotin acaricide.
    Fenbutatin oxide
  • HY-N9194
    5-Methoxycanthin-6-one
    5-Methoxycanthin-6-one is an orally active inhibitor of Leishmania strains. 5-Methoxycanthin-6-one shows cytotoxicity with an IC50 of 5.44 μg/mL against Ailanthus altissima cells.
    5-Methoxycanthin-6-one
  • HY-126812
    Longestin
    		Inhibitor
    Longestin (KS-505a) is a specific inhibitor of phosphodiesterase with antitrypanosomal activity, which is derived from Streptomyces argenteolus. Longestin is promising for research of anti-amnesia agent.
    Longestin
  • HY-163997
    Antimalarial agent 42
    		Inhibitor
    Antimalarial agent 42 (Compound 2) is an antimalarial agent, that inhibits Plasmodium falciparum in the phase of asexual blood stages (IC50 <0.5μM) and gametocytes (IC50 is 0.14 μM).
    Antimalarial agent 42
  • HY-109077S
    Tigolaner-d4
    Tigolaner-d4 is deuterium labeled Tigolaner. Tigolaner (BAY-1272858) acts on γ-aminobutyric acid (GABA) and glutamate-gated chloride channels. Tigolaner has antiparasitic activity.
    Tigolaner-d<sub>4</sub>
  • HY-136450S1
    Triclabendazole sulfoxide-13C,d3
    		Inhibitor
    Triclabendazole sulfoxide-13C,d3 is the 13C- and deuterium labeled Triclabendazole sulfoxide. Triclabendazole sulfoxide (TCBZ-SO) is the main plasma metabolite of Triclabendazole, and exhibits anti-parasite effects. Triclabendazole sulfoxide can inhibit membrane transporter ABCG2/BCRP[1][2].
    Triclabendazole sulfoxide-<sup>13</sup>C,d<sub>3</sub>
  • HY-B0817S
    Pyridaben-d13
    Pyridaben-d13 is the deuterium labeled Pyridaben[1]. Pyridaben is a mitochondrial electron transport inhibitor (METI) acaricide that promotes the formation of damaging oxygen and nitrogen radicals. Pyridaben selectively inhibits complex I (NADH dehydrogenase) with an IC50 value of 2.4 nM (assay sites: rat liver and bovine heart mitochondria). Pyridaben also significantly inhibits rat mitochondrial mtNOS function[2][3].
    Pyridaben-d<sub>13</sub>
Parasite Isoform Comparison

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